M2- tumor associated macrophages promote cancer cell growth by secreting cytokines and chemokine that promote cancer cell proliferation while simultaneously secreting chemicals that suppress the immune system from recognizing and destroying the tumor.

 The Pienta laboratory is actively studying how to selectively target M2-tumor associated macrophages for destruction as a therapy for multiple cancers.

The Pienta laboratory is actively studying how to selectively target M2-tumor associated macrophages for destruction as a therapy for multiple cancers.